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PIPELINE

Marketed Products

Two innovative therapies utilizing Kala’s proprietary AMPPLIFY® Drug Delivery Technology to address medical needs for front of the eye

EYSUVIS™ (loteprednol etabonate ophthalmic suspension) 0.25%

First and only prescription therapy specifically for the short-term management
of the signs and symptoms of dry eye disease

Inveltys (loteprednol etabonate ophthalmic suspension) 1% THERE IS NO GENERIC EQUIVALENT

First and only BID corticosteroid indicated for the treatment of post-operative ocular inflammation and pain

Development Pipeline

Proprietary development programs targeted to address front and back of the eye diseases

Product Candidate* Classification Preclinical Phase 1 Phase 2 Phase 3
KPI-012:
Mesenchymal
Stem Cell (MSC) Secretome
Persistent Corneal Epithelial Defect (PCED)(Phase 1)
Biologic
KPI-287: Tyrosine Kinase Inhibitor
Retinal diseases, including wet AMD, DME, and RVO (Preclinical)
NCE
Selective Glucocorticoid
Receptor Modulator (SEGRM)
Retinal diseases, including wet AMD, DME, and RVO;
ocular surface diseases
(Preclinical)
NCE

*Product candidates are investigational and have not been approved by any regulatory authority.

NCE – New Chemical Entity

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